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FEBS Lett, 1989
In DUAL-1 the A1c reduction from baseline with IDegLira was somewhat higher (estimated difference of 0.21%) in patients in use of pioglitazone and metformin compared to those with metformin alone (A1c for IDegLira 1.8% in the metformin subgroup and 2.1% in the metformin plus pioglitazone subgroup
Because orforglipron is a small molecule, it doesnt require the complex biological manufacturing or cold-chain logistics that peptide drugs like semaglutide demand
Will a primary care doctor prescribe Semaglutide GLP-1
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