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Conversely, we observed that primary and metastatic tissue in the GLP-1R-low group shared several immune-related genes ( Supplementary Figure 3b

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additionally, alcar raised the transcription of grm2 gene encoding for the mglu2 receptor via increasing the levels of acetylated h3k27 bound to the grm2 promoter and gaining the acetylation of nf-kb-p65 subunit