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Role of metformin, Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors, Glucagon-Like Peptide-1 (GLP-1) receptor agonists, and orlistat based multidrug therapy in glycemic control, weight loss, and euglycemia in diabesity:A real-world experience

However, supplementation with 0.1 mM Epitalon notably reduced the incidence of fragmentation from 13% in the aged group to 5.8%

Therefore, the clearance of senescent cells through apoptosis is one of the proposed mechanisms to reduce the burden imposed by the presence of senescent cells and in consequence, prevent age-related diseases and ultimately revert aging 3

This natural presence suggests inherent compatibility that synthetic compounds lack

Doses should be moderate and supervised

appropriate doseresponse controls are recommended