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But what exactly makes this combination so effective

As with treatment for hypertension or diabetes, chronic conditions require ongoing therapy

Metabolic factors including insulin resistance, thyroid function, and hormonal status affect weight loss response

Weight management A 2018 meta-analysis of randomized, placebo-controlled trials found that lipoic acid supplementation in those with high body mass index (BMI) resulted in significant, yet modest, reductions in weight (9 studies) and BMI (11 studies) in the absence of caloric restriction (except in one study) (105)

Multivariable association discovery in population-scale meta-omics studies