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If symptoms resolve with discontinuation and recur with rechallenge, alternative diabetes or weight management therapies should be considered

Complementary modeling studies suggest that GLP-1 RAs such as semaglutide and tirzepatide may disrupt the typical feedback loop in which weight loss leads to compensatory increases in appetite, potentially extending the period of reduction before plateauing occurs

This could lead to fluctuations in thyroid hormone levels, requiring close monitoring and possible adjustments in medication dosage

Diabetes Care 39(2):198205

Your medication is coordinated, your questions are answered, and your journey is fully supported from start to finish

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