Kojic acid will give you fast results on dark spots, but glutathione gives you whitening that lasts longer
Toxicity of acrylonitrile in a research-subject neuroblastoma cell line and its effect on glutathione and glutathione-S-transferase
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Kocer I, Taysi S, Ertekin MV, Karslioqlu, Gepdiremen A, Sezen O, Serifoqlu K
Boxplots showing the concentrations (y-axis) of the significantly altered metabolites in control (n = 9), compared to 50 (n = 9), 35x6 (n = 9), and 4+1 (n = 9) treatment groups analyzed by one-way ANOVA, p-value 0.1)
Though, recently it has been pointed out that the molecular pathways controlled by these two transcription factors not only are highly overlapping, with Nrf2 able to modulate genes involved in lipid metabolism and LXR involved in the promotion of glutathione transferase, but they are also mutually interconnected 38,39,40