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Most patients start noticing a reduction in appetite and experience a sense of fullness after meals within the first few weeks
GLP-1 drugs enhance this response, which can be particularly helpful among people with type 2 diabetes, who may have a reduced natural GLP-1 response
The fourth is body composition trend - not just scale weight
Gerstein HC, Colhoun HM, Dagenais GR et al (2019) Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial
They with an NSAID avoided the increase in gut permeability seen in the placebo group
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