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Uric acid demonstrates neuroprotective effect on Parkinsons disease mice through Nrf2-ARE signaling pathway

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Metformin treatment should not be discontinued

10.1016/j.csbj.2019.09.004 7 BecharaC.PallerlaM.ZaltsmanY.BurlinaF.AlvesI

14: Bajramagic S, Sever M, Rasic F, Staresinic M, Skrtic A, Beketic Oreskovic L, Oreskovic I, Strbe S, Loga Zec S, Hrabar J, Coric L, Prenc M, Blagaic V, Brcic K, Boban Blagaic A, Seiwerth S, Sikiric P

As a model for physiological conditions the cancer cells were cultivated and treated with a 21% O 2 atmosphere, and as a model for hypoxic conditions the cancer cells were cultivated and treated with a 1% O 2 atmosphere