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Glutathione deficiency and oxidative stress have been implicated in the pathogenesis of neurological diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis

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At the same time, social media influencers and advertisements have fueled demand from not only people who have diabetes or are overweight or obese, but also those who may want to take these drugs for cosmetic reasons, such as to shed a few pounds

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Additionally, real-world pharmacovigilance data highlight sensory adverse events (particularly dysgeusia) that appear more frequently in clinical practice than in controlled trials, suggesting under recognition of taste-related disturbances in research settings (159)