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Functional eNOS dimer catalyzes the electron transfer from the C-terminal-bound NADPH through FAD and FMN of one monomer to the heme iron in the N-terminal oxygenase domain of the second monomer, and this interdomain electron transfer is facilitated by CaM

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A lack of vitamin B12 is treated with methylcobalamin

* Correspondence: Xin Xu, [email protected] ORCID: Xin Xu, orcid.org/0000-0002-7216-3787 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers