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It is important to appreciate, however, that the increased risk relates to a disorder that is relatively uncommon. NAION is the second-leading cause of optic nerve blindness NAION is relatively rare, occurring up to 10 out of 100,000 people in the general population

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Many reports showed that GLP-1 effects involve neural modulation and peripheral effects, which increase satiety, resting energy expenditure and lower plasma concentrations of free fatty acids [20]-[22]

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Effects of pentadecapeptide BPC 157 on experimental rat model of dry eye