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Impaired individuals exhibit hypomethylation of CpG sites in the CCL11 promoter region, which are then hypermethylated upon supplementation with B12 In impaired individuals, three CpG sites exhibited hypomethylation when compared to the non-impaired group

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Key Findings (Chronic): Fat Loss Without Eating Less Lower Body Weight and Adipose Tissue in Obese Mice In ob/ob mice, both AOD9604 and hGH decreased body weight and epididymal white adipose tissue mass (AOD9604 by approximately 28%, hGH by approximately 40%)

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