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A phase III, randomized, placebo-controlled, double-blind study of 353 patients with colon cancer receiving adjuvant FOLFOX (leucovorin, fluorouracil and oxaliplatin) randomly assigned to intravenous calcium/magnesium before and after oxaliplatin showed no significant reduction in oxaliplatin-induced acute neuropathy, and the results of this study did not support the use of calcium/magnesium to prevent CIPN [115]

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Bacterial lipopolysaccharide inhibits free thiamin uptake along the intestinal tract via interference with membrane expression of thiamin transporters 1 and 2

The role of the glutathione antioxidant system in gut barrier failure in a rodent model of experimental necrotizing enterocolitis