An increased level of Nrf2 expression resulted in lower survival and increased cancerous cell progression and proliferation in breast cancer patients (Almeida et al., 2020)
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It should be noted that men with known conditions that would cause inflammation (such as genital tract infections, varicocele) or that used alcohol, smoked, or were currently taking antioxidants were all excluded from the study to create a more consistent base-line of existing oxidative stress (inflammation) between the groups This study also showed that the higher the measured levels of ROS, the more damage there was to sperm function
Homeostatic regulation of protein intake: in search of a mechanism