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sustained) Comparative PK/PD: Short-acting GHS vs
10.1089/ars.2020.8141 68
An observational cohort study involving 168 pregnant women exposed to GLP-1 receptor agonists during the first trimester found a 2.6% prevalence of major birth defects, comparable to 2.3% in the diabetic reference group
The cost of GLP-1s coupled with the number of patients in the United States who meet newly expanded indications has led the healthcare insurance industry to limit coverage in many situations despite patients presenting with indications approved by the FDA
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