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10.1016/b978-0-12-813442-9.00007-9 25 HeubergerJ

If absorption issues are suspected, additional testing may be appropriate

It involved three primary steps: (1) Liposome freezing with a cryoprotectant, (2) Primary drying and sublimation, and (3) Secondary drying to remove the remnant moisture [162]

For instance, replacing problematic functional groups, such as the carboxylic acid group in danuglipron, with alternative structures has shown promise

In addition, Eli Lilly has several follow-on patents granted for delivery devices, formulations, and methods-of-treatment