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NNMT depletes NAD+ by converting nicotinamide (a NAD+ precursor) into 1-methylnicotinamide

& Hayward, G

2015;21(11):13506 (Epub 2015/10/13)

Keeping up with your daily caloric needs is important while taking this drug, and if not achieved can make you feel sluggish

Protocol Quick-Reference PRECLINICAL ONLY: NNMT inhibition research compound Dosing Amount No established human dose (mouse: ~34 mg/kg/day SC) Frequency No established human frequency Duration No established human duration Administration Route Oral Schedule N/A (preclinical compound) Timing NO HUMAN DOSING DATA EXISTS

180,183 Finasteride is also known for its inhibitory effect on 5-R1