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A critical distinction exists between direct pharmacological effects on psoriasis and indirect benefits from weight loss itself
At the same time, the lowest dose of tirzepatide (5mg) reduced body weight by 17.2 lbs and A1C by 2.09% compared to 13.7 lbs weight loss and 1.86% reduction in A1C on using semaglutide
However, rapid weight loss combined with muscle loss may temporarily destabilize the spine until strength is rebuilt
This may be further pronounced in patients with diabetes with compromised gastrointestinal function due to autonomic neuropathy
If there was a main effect, the Bonferroni correction was used
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