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Conversely, decreased Cav-1 level or obstructed Cav-1 and eNOS interaction can release eNOS favoring its activation and induction of nitric oxide production that is known for its protective effect on vessels 44,45
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Thus, ozone therapy can be a new therapeutically approach for atopic asthma thanks to its immunomodulation and oxidative stress regulation properties
EPCs contribute to postnatal vasculogenesis, and are recruited from the bone marrow to sites of injury via growth factors, cytokines and hypoxia-related signaling pathways, where they differentiate into mature endothelial cells and incorporate themselves into sites of active neovascularization [41, 51]
The high initial GFP intensity levels observed immediately after DEM exposure could be attributed to a delay of approximately 20 min between the addition of DEM and image acquisition (Fig