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For patients taking warfarin or other coumarin derivatives, more frequent monitoring of INR (International Normalised Ratio) is recommended when starting semaglutide treatment, as weight loss and dietary changes can affect drug metabolism and effectiveness

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doi: 10.1016/j.chom.2014.02.005 85 MachielsKJoossensMSabinoJDe PreterVArijsIEeckhautVet al