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The trial period was 12 weeks and the dose was 60 mg/kg/day in three doses with a maximum of 4,200 mg/day
Research shows GLP-1 medications may help reduce cravings and prevent relapse
A meta-analysis of five RCTs (over 4,400 people) in Endocrinology, Diabetes & Metabolism found that GI side effects were significantly more common at orforglipron doses of 12 mg or higher
Now for the GLP-1 connection
Lam, Li Long (2007)
These results support the hypothesis that GLP-1 agonists may simultaneously target alcohol use disorders and physical comorbidities such as obesity and metabolic syndrome
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