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It is not approved for therapeutic use and is intended strictly for laboratory and investigative research purposes

In the absence of safety data, most clinicians advise that pregnant or breastfeeding individuals avoid this compounded preparation unless the anticipated benefit clearly outweighs theoretical fetal or neonatal risks

Trimethylaminuria (Fish Odor Syndrome)

After a B12 shot, blood levels rise well above the desired range (150-700 pmol/L in most places), and stay high for a while

This article explains how these injections work, their benefits and risks, and how they compare to taking B12 in pill form

Kidney disease or renal insufficiency, where amino acid overload may pose a risk