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hypothesized that elevated triglyceride (TG) levels could function both as a biomarker for major depression and as a contributor to its pathogenesis, possibly via dual pathways involving metabolic dysfunction and neuroinflammation ( In addition, ketone body (KB), a metabolite of TG in the liver, may also influence MDD ( Collectively, the evidence derived from both observational and mechanistic studies indicates a potential association between elevated triglyceride (TG) levels and depression, as systematically outlined in Table 1

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These are all crucial for effective immune response

Researchers who maintain consistent exercise routines while on retatrutide often see their resting heart rate stabilize or decrease below baseline over months, despite the drug effect

Instead, they are illustrative examples of experimental data from in vivo and in vitro and rodent and nonrodent studies