The most parsimonious hypothesis is simply that this is a case of a viral protease targeting a cellular gene for cleavage, for which there are abundant precedents, including the proposed M pro targeting of TRMT1 and HDAC2 (9), and HIV-1 protease, which can be toxic to cells, via its action at various cellular targets (15)
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Mucosal & Endothelial Protection Assays: Evaluating the combined efficacy of this tri-blend in protecting sensitive cellular monolayers from hypoxic conditions or induced oxidative stress
About this article Cite this article Tang, L., Wang, W., Zhou, W