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10.1002/1878-0261.12039 Mol
Zandifar, A., Seifabadi, S., Zandifar, E., Beheshti, S
Severe constipation : No bowel movement for more than 34 days despite home management, or inability to pass gas
Hashemi sJ, Chobineh M, Moghaddam E
It binds and unbinds in a constant exchange, so some free copper ions escape and irritate local nerve endings while activating mast cells (immune cells that release histamine and trigger inflammation)
Its not laid out very clearly, but the guarantee requires you to try the product for 60 days before returning two opened containers for your money back
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