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nonetheless, these assertions remain based on preclinical findings
A 2024 study reported that many people feel a boost in self-confidence after losing significant weight
doi: 10.1172/jci.insight.123182 172 LiuZ.RenZ.ZhangJ.ChuangC.-C.KandaswamyE.ZhouT.et al
Although GLP-1RAs seem to have a beneficial influence in reversing many maladaptive brain changes relevant to depression, it should be remembered that at the same time, they are also known to mediate some unfavorable processes such as activation of the HPA axis and intensification of anxiety-like behavior in some animal studies
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