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The ability to obtain the compound through legitimate medical channels also provides quality assurance benefits, as regulated pharmacies must meet standards for purity and potency that unregulated suppliers do not

The review will adhere to the methodology outlined in the Joanna Briggs Institute Reviewers Manual [2], and will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) [8]

With 8,847 participants over eight randomized controlled trials (RCTs), it was shown that 375 out of 1,000 people lost 10% of their body weight over the course of two years, with a net benefit probability of 0.91 in the second year and 0.97 in the first

It also serves as a cofactor for detoxifying enzymes

It's worth noting that magnesium and calcium supplements can reduce the absorption of certain medications, including levothyroxine and some antibiotics

16 July 2026