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Riaz TA, Junjappa RP, Handigund M, Ferdous J, Kim HR, Chae HJ (2020) Role of endoplasmic reticulum stress sensor IRE1 in cellular physiology, calcium, ROS signaling, and metaflammation

Sima Chokr, PhD (Thompson Lab), discussed how brain immune cells may influence disease processes in Huntingtons disease

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For in vivo experiments, colistin and L-carnitine were dissolved in PBS on each treatment day prior to injection

Epigenetic and Cellular Reprogramming: By blocking NNMT-mediated methylation of nicotinamide, preserves NAD salvage pathway activity, increases SIRT-1 signaling, reduces histone deacetylation, and promotes metabolic reprogramming toward oxidative phosphorylation and glycolysis balance, supporting tissue repair and energy homeostasis 1-4