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To test LaccID in a similar manner, we created an ER-targeted construct by appending a KDEL ER retention sequence and prepared analogous constructs for APEX2 and HRP for comparison

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The prognostic difference among the clinical types of melanoma relates mainly to the duration of the radial growth phase, which may last from years to decades in LMM, from months to 2 years in SSM, and 6 months or less in NM

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