An 8-week treadmill exercise at 70%85% VO 2 max significantly downregulated the levels of TFR1, TF, DMT1, FTL, FTH, mitochondrial Ferritin, -secretase, and APP in the cortical motor regions of aged amyloid precursor protein-C105 (APP-C105) mice, upregulated the expression of FPN1, Furin, and -secretase, significantly reduced Fe 2+ , Fe 3+ , and total iron content, inhibited brain iron accumulation and A plaque growth, thereby improving learning ability, memory, and cognitive function in aged APP-C105 mice (Choi et al., 2021)
While awaiting your specialist evaluation, it is wise to discuss with your doctor whether you should temporarily dial back intense exercise routines to play it safe
In fact, L-citrulline increases levels of L-arginine in your body more than supplementing with L-arginine itself does
Healthy Weight Loss Maintenance With Exercise, GLP-1 Receptor Agonist, or Both Combined Followed By One Year Without Treatment: A Post-Treatment Analysis of a Randomised Placebo-Controlled Trial
Your provider will help determine the best option for your needs and lifestyle
Due to its regulatory rather than stimulatory mechanism, Epithalon is considered suitable for long-term longevity support when used in structured cycles