The protective function of RESV and the contribution of TRPV4 to streptozotocin (STZ)-induced neuropathic pain in mice are still unclear
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AQP4 dysregulation contributes to several other CNS disorders
This reinforces the need for carefully titrated regimens, especially in clinical settings where circadian timing (chronopharmacology) may dictate efficacy
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23 In Enterobacteriaceae , a variety of -lactamases, including extended-spectrum -lactamases (ESBLs) and carbapenemases (KPC, NDM, VIM, OXA), are present and confer resistance against last-resort antibiotics like carbapenems