doi: 10.18632/oncotarget.8063 106 YangQWangXTangCChenXHeJ
Ozeki et al (2022) found that GLP1-RA semaglutide effectively reduces body adiposity while maintaining the skeletal muscle mass in obese Type 2 Diabetic patients. Xiang et al (2023) had similar findings, semaglutide can reduce the weight and fat of obese patients while effectively maintaining muscle mass and muscle strength. Chen et al (2023) conducted a 3-month intervention using dulaglutide in patients with Type 2 Diabetes, noting , dulaglutide intervention does not cause muscle and bone mass loss while inducing weight loss, and % change in body fat was independently associated with improved glucose control during dulaglutide therapy. With an increasing number of physicians and researchers relying on GLP-1 therapies for clinical care and research, it will continue to be crucial to track sensitive changes in body composition across different patient populations
Nutritional and Lifestyle Guidance Medical weight loss is not medication alone
This can include changes in the concentration of the active ingredient, the addition of other substances, or modification of the delivery method
Prescriptions are issued solely at clinician discretion and, when authorized, are routed to a partner pharmacy for fulfillment
Finding the Right Balance for Your Goals If your primary goal is general wellness and healthy ageing, a lower daily dose of both may be sufficient