GHK-Cu can be a powerful tool but it works best as part of a complete healing strategy
in this case, all individuals (or majority) living in a given area are exposed to iodine excess
A common example is the Cathepsin B-sensitive linker (such as the Val-Cit peptide), which is cleaved in the lysosomal environment by Cathepsin B, rapidly releasing the drug
Bliddal H, Leeds AR, Christensen R (2014) Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review
A typical protocol for this stack is 4 to 6 mg weekly of Retatrutide (starting at 1 mg on the first injection and escalating slowly) and 2 to 3 mg of KLOW daily
In DIO mice and obese monkeys, AMG133 decreases fasting insulin levels, but this effect was not seen in the clinical trial of AMG133 (84)