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This phenomenon is not unique to GLP-1splateaus happen in any regimen, including diets, exercise, and bariatric surgery

These effects typically emerge within the first 1-2 weeks and often diminish over 4-8 weeks, though individual variation is substantial

A beneficiary with a BMI of 32 and uncontrolled hypertension, or a BMI of 28 with pre-diabetes and a prior stroke, previously had no straightforward path to GLP-1 coverage

This article examines current evidence regarding GLP-1 and cortisol regulation, clarifies what these medications can and cannot do, and outlines appropriate approaches for managing cortisol-related metabolic concerns

doi: 10.1016/j.neulet.2017.06.052 47

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