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However, one study on the treatment of children with methylmalonic acidemia and homocystinuria found oral hydroxocobalamine at 1 mg daily to be ineffective in reducing levels of homocysteine
(Source 9) Liposomal glutathione in doses up to 1000 mg per day is generally safe, and side effects are rare, although we dont recommend taking glutathione during pregnancy or breastfeeding
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How long this lasts depends on how well the patient responds and the severity of the deficiency
An increase in intracellular glutamate associated with a decrease in NAA may be specific to ALS, as it has not been consistently reported in other neurodegenerative diseases that are accompanied by a decrease in NAA levels