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Ferroptosis is regulated by lipid repair enzymes, which also include GSH and GPx4 reducing lipid hydroperoxides (L-OOH) to lipid alcohols (L-OH) 601

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By contrast, we found in the model (simulations not shown) that the blood concentrations of GSH and GSSG track the intracellular concentrations

When TFAM is phosphorylated by cyclic adenosine monophosphate (cAMP)-dependent protein kinase, its ability to bind mtDNA and activate transcription is diminished, leading to the rapid and selective degradation of unbound TFAM by LONP1 [53]