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What the research says about muscle preservation during GLP-1 therapy
However, the RCTs analyzed suffer from use of different comparators and short follow-up durations (median durations between 12 weeks and 2 years), and any beneficial effects on fracture rates on such short time-scales may be due to a lower risk of falling rather than improved bone quality
Three small cohort studies 148,149,150 examined associations between GLP-1RA use and metabolic changes in adults with a diagnosis of schizophrenia and comorbid diabetes and/or obesity on antipsychotics
The primary benefit is better body composition, not just faster weight loss
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