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A 2017 meta-analysis of data from 15 trials, including more than 71,000 participants at risk of or with existing CVD, showed that B-vitamin supplementation had no significant effect on risk of myocardial infarction (heart attack) or all-cause mortality but reduced risk of stroke by 10% (RR, 0.90

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As an alternative, tributyrin supplementation in diet-induced obese mice was also shown to improve glucose tolerance and inflammatory status (86), indicating that direct supplementation of butyrate might have beneficial effects on both metabolic and inflammatory parameters relevant for the pathophysiology of T2D

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Are these drugs just a short-term solution? For those who may be taking or considering a GLP-1 receptor agonist, all experts agree it is important to go through a physician who will continuously monitor them and keep them updated on any side effects they may experience