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Some people use lower doses during breaks rather than complete discontinuation, but this strategy lacks clinical validation
Clinical trial has been completed on a novel micelle-encapsulated doxorubicin formulation (NK911) with high efficacy and minimum toxicity (112)
However, MT activity toward cardiac Akt2 function by inhibiting TRB3 can prevent DCM [20]
doi: 10.1038/ijo.2011.158 89 AstrupARssnerSVan GaalLRissanenANiskanenLAl HakimMet al
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