This includes patients who have problems related to the ileum which is the final section of the small intestine, such as Crohns disease
More serious, though rare, side effects can occur, such as symptoms of low potassium levels (muscle cramps, weakness, irregular heartbeat) or signs of an allergic reaction
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It could point to several things: A different cause: your fatigue might stem from thyroid problems, iron deficiency, or sleep apnea rather than B12
Anemia from another cause, thyroid disease, iron deficiency, folate deficiency, inflammatory disease, and metabolic contributors can all produce overlapping complaints, as can medication effects, sleep disorders, and neurologic conditions
Some doctors even use B12 to treat psoriasis and eczema