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However, the generation of ATP as an energy source in the mitochondria induces oxidative stress caused by increased ROS production, resulting in cell death [11,22,23]

Safety Profile of Combination Therapy The safety profile of combined SGLT2i and GLP-1RA therapy is broadly consistent with the known adverse effects of each class, without evidence of novel or synergistic toxicity [11, 26,27,28,29,30]

Acetyl-L-carnitine induces a sustained potentiation of the afterhyperpolarization

Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression

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