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pylori -infected mouse model, a functional Nrf2 pathway was found to be required for the reduction of gastric inflammation and infection in mice fed broccoli sprouts (50)

In the 1970s, clinical trials on patients with terminal cancer showed that intravenous high-dose ascorbate treatment, that achieved a peak plasma concentration of 6 mM, extended their survival (143, 144), whereas in the 1980s they failed to confirm these findings because ascorbate was given at the same dose orally and the peak plasma concentration was of less than 200 M (145, 146)

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CCR5 is a therapeutic target for recovery after stroke and traumatic brain injury