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During thawing, local concentration gradients and interfacial stress promote aggregation of peptide chains
It is manufactured by solid-phase synthesis, typically as a research chemical
Improper mixing may cause unstable solutions with reduced biological effectiveness
In America, B12 deficiency is evidenced as a serum level below 200 pg/ml (145 pM)
Thus, one must consult their registered doctor to screen for deficiency and start supplementation only after receiving advice from their doctor
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