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On a global scale, over 1.2 million new cases are diagnosed every year

It appears in human plasma at approximately 200 ng/ml in young subjects, with a drop of more than 60 % between ages 20 and 60, an observation that motivated forty years of research on its role in tissue repair, wound healing, hair growth and cutaneous longevity

Its levels fall with age, so a supervised plan can help rebuild firmness and reduce shedding gradually

The mice treated in this manner appeared to remain very healthy and active, in contrast to the toxicities of current cancer chemotherapy

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However, the effect varies, is not guaranteed, and the evidence is still limited