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4.0 Future therapeutic opportunities in neurodegenerative diseases Recent clinical and preclinical evidence has established the potential of incretin mimetics to target pathological features central to neurodegenerative disorders
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[0007] WO2007/0611434 described pharmaceutical compositions of intranasal exenatide using similar formulation technologies in WO2007/146488, plus a dipeptidyl aminopeptidase (DPP) IV inhibitor to minimize enzymatic degradation of exenatide
We also did this because the effect of SGLT2i on the primary MACE outcome was not available or pooled in a published meta-analysis for all completed SGLT2 inhibitor outcome trials
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