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How Zepbound Doses Are Adjusted Your healthcare provider will increase your dose every four weeks until you reach the recommended maintenance dose, which varies depending on how your body responds to the medication and your reason for using Zepbound: For weight loss, the maintenance dosage is 5 mg, 10 mg, or 15 mg weekly

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Critical distinction from insulin : Insulin is dosed in "units," with U-100 insulin containing 100 units per mL

It targets the liver and adipose tissue to increase energy expenditure (thermogenesis) and promote the breakdown of stored fats

Furthermore, when the delivery rate of NEFAs inside hepatocytes exceeds the rate of intracellular -oxidation and/or formation to neutral TG, excess NEFAs can enter into harmful non-oxidative pathways