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In some of the trials on Semaglutide, 30-40% of weight loss was the fat-free mass

Additionally, it has been reported that GLP-1 analogues may inhibit markers of eosinophil activation and the production of Th2 cytokines

, Efficacy and safety of once-weekly semaglutide monotherapy versus placebo in patients with type 2 diabetes (SUSTAIN 1): a double-blind, randomised, placebo-controlled, parallel-group, multinational, multicentre phase 3a trial, Lancet Diabetes Endocrinol

PLoS ONE 10 , e0120074 (2015)

Lipid glycation and protein glycation in diabetes and atherosclerosis

It also interferes with estrogen metabolism, throwing your hormones off balance and encouraging even more belly fat to accumulate