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Initial Loading Dose Protocol For severe deficiency, the first dose is usually 1,000 mcg given intramuscularly

Protection from light is also specified because UV radiation can photo-reduce Cu(II) to Cu(I), which has different coordination chemistry and generates reactive oxygen species that degrade the peptide backbone

Contains zinc which may be dangerous if taken in large amounts or for a long period

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To address these challenges, future research should prioritize longitudinal cohort designs to clarify the temporal sequence between microbiome alterations and HPV infection