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Some potential risks of skin whitening include: Skin irritation or itching Redness Uneven skin tone Squamous cell carcinoma Skin thinning Acne breakouts Increased sensitivity to sunlight Liver, kidney, or nerve damage Blue-black pigmentation due to ochronosis disorder

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Imaging studies, where employed, may show tissue changes during mid-phase

Husain GM, Chatterjee SS, Singh PN, Kumar V

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Cerebrospinal fluid (CSF) metabolite data The cerebrospinal fluid metabolite data were sourced from the Wisconsin Alzheimers Disease Research Center (WADRC) and the Wisconsin Registry for Alzheimers Prevention (WRAP) longitudinal cohort studies