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GLP-1 RAs, such as tirzepatide and semaglutide, have become widely used to treat obesity and type 2 diabetes

The company built its proprietary Precision Endocrine Peptide (PEP) platform to engineer peptide hormones with extended time-action profiles, aiming to overcome the dosing-frequency and tolerability limitations of earlier peptide therapeutics, including in the obesity space

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(b) semaglutide total exposure was not influenced, but semaglutide maximum concentration was higher and occurred earlier, when combining semaglutide with icodec in IcoSema relative to semaglutide administration alone

We are getting a better understanding of the complex factors that influence obesity, says Plata